Research

Re-think | Re-invent

Research Areas

Establishing close interactions among a group of researchers with very different backgrounds, expertise, and approaches requires some form of common intellectual focus and interest. Given the necessary and present methodological diversity within QBM, the focus is on one fundamental and encompassing biological problem – the control of gene expression in all its aspects, and the interplay of the different control mechanisms in regulatory networks.

The participating biochemists (Baumeister, Becker, Beckmann, Conti, Gaul, Hartl, Herzog, Hopfner, Imhof) study the molecular mechanisms of gene regulation in all its aspects, ranging from transcription to RNA transport and degradation, and from translation to protein folding, transport and degradation.

The biophysicists participating in QBM (Braun, Jungmann, Rädler, Schwille) bring a wealth of advanced expertise and novel methodologies, permitting the high-resolution quantitative and dynamic analysis of regulatory processes, including protein folding/conformation and the interaction of proteins with small molecules, nucleic acids, or other proteins in different settings (single molecule, purified/crude extracts).

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